Blocing of URL independent of browsers

hi guyz

i have been searching ways to block urls using symantec and i have applay polices on my SEPPM and blocked myny wensites. but i was woundering is there a way to block URLs without defining browsers ? i mean if i block www.facebook.com it is blocked on all the browsers without defining them one by one.

i am using SEPM 12.1.3.